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Forster (Fluorescence) Resonance Energy Transfer (FRET) Microscopy Typical fluorescence microscopy techniques rely upon the absorption by a fluorophore of light at one wavelength (excitation), followed by the subsequent emission of secondary fluorescence at a longer wavelength. The excitation and emission wavelengths are often separated from each other by tens to hundreds of nanometers. Using this technique, molecules that are closer together than the optical resolution limit appear to be coincident.
Limitations in determination of the spatial proximity of protein molecules can be overcome by applying Forster (or Fluorescence) Resonance Energy Transfer (FRET) microscopy techniques. FRET occurs between two appropriately positioned fluorophores only when the distance separating them is 8 to 10 nanometers or less. Thus, FRET is well-suited to the investigation of protein interactions that occur between two molecules positioned within several nanometers of each other.
Forster (Fluorescence) Resonance Energy Transfer (FRET) Microscopy Lasers
| Product | Wavelength | Description | Starting At | In Stock | |
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 | 405 nm Best Seller! | 405 nm Collimated Diode Laser System 50 - 10000 mW Output Power | $991.00 | Specs |
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 | 532 nm Best Seller! | 532 nm DPSS Laser System 5 - 300 mW Output Power | $1,437.00 | Specs |
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 | 473 nm Best Seller! | 473 nm DPSS Laser System 5 - 100 mW Output Power | $1,664.00 | Specs |
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 | 450 nm | 450 nm Collimated Diode Laser System 5 - 1000 mW Output Power | $1,781.00 | Specs |
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 | 450 nm | 450 nm Low-Noise Collimated Diode Laser System 5 - 1000 mW Output Power | $1,982.00 | Specs |
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 | 635 nm Best Seller! | 635 nm Collimated Diode Laser System 5 - 500 mW Output Power | $2,225.00 | Specs |
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 | 1064 nm Best Seller! | 1064 nm Low-Noise DPSS Laser System 100 - 1000 mW Output Power | $2,274.00 | Specs |
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 | 405 nm Best Seller! | 405 nm Low-Noise Collimated Diode Laser System 5 - 500 mW Output Power | $2,275.00 | Specs |
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| 473 nm Best Seller! | 473 nm DPSS Laser System 200 - 500 mW Output Power | $2,482.00 | Specs |
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| 450 nm | 450 nm Collimated Diode Laser System with Near-TEM00 Beam 5 - 50 mW Output Power | $2,583.00 | Specs |
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| 635 nm Best Seller! | 635 nm Collimated Diode Laser System with Near-TEM00 Beam 5 - 200 mW Output Power | $2,583.00 | Specs |
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 | 510 nm | 510 nm Collimated Diode Laser System 5 - 30 mW Output Power | $2,625.00 | Specs |
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| 450 nm | 450 nm Collimated Diode Laser System 1500 - 3500 mW Output Power | $3,060.00 | Specs |
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 | 671 nm Best Seller! | Fanless 671 nm DPSS Laser System 300 - 1000 mW Output Power | $3,060.00 | Specs |
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 | 515 nm | 515 nm DPSS Laser System 10 - 50 mW Output Power | $3,167.00 | Specs |
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 | 532 nm Best Seller! | 532 nm Low-Noise DPSS Laser System 5 - 200 mW Output Power | $3,296.00 | Specs |
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 | 510 nm | 510 nm Low-Noise Collimated Diode Laser System 5 - 30 mW Output Power | $3,498.00 | Specs |
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 | 561 nm | Fanless 561 nm DPSS Laser System 5 - 200 mW Output Power | $3,600.00 | Specs |
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 | 473 nm Best Seller! | Fanless 473 nm Low-Noise DPSS Laser System 5 - 500 mW Output Power | $3,749.00 | Specs |
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| 532 nm Best Seller! | Fanless Fanless 532 nm DPSS Laser System 500 - 1000 mW Output Power | $4,104.00 | Specs |
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 | 543 nm | 543 nm DPSS Laser System 20 - 100 mW Output Power | $4,104.00 | Specs |
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 | 400 nm | 400 nm Low-Noise Collimated Diode Laser System 5 - 300 mW Output Power | $4,190.00 | Specs |
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| 473 nm Best Seller! | Environmentally Sealed 473 nm DPSS Laser System 10 - 100 mW Output Power | $4,225.00 | Specs |
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 | 750 nm | 750 nm Low-Noise Collimated Diode Laser System 100 - 2000 mW Output Power | $4,238.00 | Specs |
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 | 500.8 nm | 500.8 nm DPSS Laser System 1 - 2 mW Output Power | $4,421.00 | Specs |
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 | 491 nm | 491 nm DPSS Laser System 1 - 2 mW Output Power | $4,430.00 | Specs |
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| 1064 nm Best Seller! | 1064 nm Low-Noise DPSS Laser System 2000 - 2000 mW Output Power | $4,485.00 | Specs |
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| 532 nm Best Seller! | Environmentally Sealed 532 nm DPSS Laser System 10 - 300 mW Output Power | $4,668.00 | Specs |
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| 405 nm Best Seller! | 405 nm Collimated Diode Laser System with TEM00 Beam 10 - 40 mW Output Power | $4,777.00 | Specs |
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| 405 nm Best Seller! | 405 nm Collimated Diode Laser System 30 - 50 mW Output Power | $4,805.00 | Specs |
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 | 488 nm | 488 nm Collimated Diode Laser System with Near-TEM00 Beam 30 - 160 mW Output Power | $4,805.00 | Specs |
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| 473 nm Best Seller! | Fanless 473 nm DPSS Laser System 5 - 500 mW Output Power | $4,805.00 | Specs |
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| 532 nm Best Seller! | 532 nm Low-Noise DPSS Laser System - mW Output Power | $5,032.00 | Specs |
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| 532 nm Best Seller! | Fanless 532 nm Low-Noise DPSS Laser System 500 - 1000 mW Output Power | $5,304.00 | Specs |
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| 532 nm Best Seller! | 532 nm DPSS Laser System 2000 mW Output Power | $5,478.00 | Specs |
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| 635 nm Best Seller! | 635 nm Collimated Diode Laser System 3000 - 6000 mW Output Power | $5,913.00 | Specs |
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 | 589 nm Best Seller! | 589 nm DPSS Laser System 10 - 50 mW Output Power | $5,913.00 | Specs |
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| 671 nm Best Seller! | 671 nm DPSS Laser System - mW Output Power | $5,913.00 | Specs |
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 | 656.5 nm | Fanless 656.5 nm DPSS Laser System - mW Output Power | $6,547.00 | Specs |
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| 532 nm Best Seller! | 532 nm Low-Noise DPSS Laser System 2000 - 2000 mW Output Power | $6,776.00 | Specs |
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| 532 nm Best Seller! | 532 nm DPSS Laser System 3000 - 5000 mW Output Power | $6,958.00 | Specs |
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| 561 nm | 561 nm DPSS Laser System 500 - 1000 mW Output Power | $6,958.00 | Specs |
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| 1064 nm Best Seller! | 1064 nm Low-Noise DPSS Laser System 4000 - 5000 mW Output Power | $7,330.00 | Specs |
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| 491 nm | 491 nm DPSS Laser System - mW Output Power | $7,594.00 | Specs |
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| 543 nm | Environmentally Sealed 543 nm DPSS Laser System | $7,720.00 | Specs |
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| 543 nm | 543 nm DPSS Laser System 200 - 1500 mW Output Power | $7,954.00 | Specs |
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| 589 nm Best Seller! | 589 nm DPSS Laser System 100 - 300 mW Output Power | $7,954.00 | Specs |
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| 473 nm Best Seller! | 473 nm DPSS Laser System 800 - 1500 mW Output Power | $8,673.00 | Specs |
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 | 395 nm | 395 nm Collimated Diode Laser System 5 - 100 mW Output Power | $9,071.00 | Specs |
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 | 660 nm | 660 nm DPSS Laser System 500 - 800 mW Output Power | $9,099.00 | Specs |
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| 532 nm Best Seller! | 532 nm Low-Noise DPSS Laser System 5000 - 5000 mW Output Power | $9,534.00 | Specs |
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| 515 nm | 515 nm DPSS Laser System 100 - 100 mW Output Power | $10,241.00 | Specs |
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| 532 nm Best Seller! | 532 nm DPSS Laser System 8000 - 20000 mW Output Power | $11,375.00 | Specs |
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| 589 nm Best Seller! | 589 nm DPSS Laser System 500 - 500 mW Output Power | $11,375.00 | Specs |
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| 589 nm Best Seller! | Environmentally Sealed 589 nm DPSS Laser System - mW Output Power | $11,375.00 | Specs |
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| 488 nm | 488 nm Collimated Diode Laser System 200 - 1800 mW Output Power | $12,947.00 | Specs |
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 | 375 nm | 375 nm Collimated Diode Laser System with Near-TEM00 Beam 5 - 50 mW Output Power | $13,589.00 | Specs |
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 | 355 nm | 355 nm DPSS Laser System 1 - 10 mW Output Power | $13,617.00 | Specs |
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| 473 nm Best Seller! | 473 nm DPSS Laser System | $13,975.00 | Specs |
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| 515 nm | 515 nm DPSS Laser System 200 - 500 mW Output Power | $13,975.00 | Specs |
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| 532 nm Best Seller! | 532 nm Low-Noise DPSS Laser System 8000 - 20000 mW Output Power | $14,383.00 | Specs |
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| 375 nm | 375 nm Collimated Diode Laser System 100 - 150 mW Output Power | $14,726.00 | Specs |
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 | 488 nm | 488 nm Low-Noise Collimated Diode Laser System with Near-TEM00 Beam 5 - 50 mW Output Power | $15,801.00 | Specs |
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| 488 nm | 488 nm Low-Noise Collimated Diode Laser System 100 - 150 mW Output Power | $15,915.00 | Specs |
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| 1064 nm Best Seller! | 1064 nm Low-Noise DPSS Laser System 10000 - 20000 mW Output Power | $16,891.00 | Specs |
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| 488 nm | 488 nm Collimated Diode Laser System 5 - 80 mW Output Power | $16,927.00 | Specs |
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| 589 nm Best Seller! | 589 nm DPSS Laser System 1000 - 3000 mW Output Power | $17,982.00 | Specs |
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| 561 nm | 561 nm DPSS Laser System 1500 - 2000 mW Output Power | $19,105.00 | Specs |
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| 671 nm Best Seller! | 671 nm DPSS Laser System 3000 - 5000 mW Output Power | $19,126.00 | Specs |
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| 375 nm | 375 nm Collimated Diode Laser System 5 - 20 mW Output Power | $20,122.00 | Specs |
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| 473 nm Best Seller! | 473 nm DPSS Laser System - mW Output Power | $20,150.00 | Specs |
Here are a list of research papers that reference Arktis Laser products in their Forster (Fluorescence) Resonance Energy Transfer (FRET) Microscopy.
| Paper Title | Date Published | University | Product Used In Research | Polymer-based gadolinium oxide nanocomposites for FL/MR/PA imaging guided and photothermal/photodynamic combined anti-tumor therapy | March 2018 | Tianjin Key Laboratory of Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University | 532 nm |
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| Development of Nanoparticle-based Platforms for Potential Applications in Biosensing and Therapeutics | December 2017 | University of Cincinnati | 685 nm |